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Mean Corpuscular Volume (MCV)

CBC
Normal range
80–100 fL
☎ When to call

Not independently critical — escalate the anemia it explains, not the MCV itself.

What you do
  • Use it to explain anemia, not to act on directly
  • Low MCV + low Hgb: think iron/chronic bleed — diet and GI history matter
Causes of HIGH mean corpuscular volume
B12 / folate deficiency (macrocytic)Alcohol useLiver diseaseHypothyroidism
Causes of LOW mean corpuscular volume
Iron deficiency (microcytic)ThalassemiaChronic blood loss
Source: Pagana, Mosby's Manual of Diagnostic and Laboratory Tests, 7th ed.Reference only — verify against your facility's policy.

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