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alteplase (tPA) HIGH ALERT

Thrombolytic
What it's for

Ischemic stroke, massive PE, STEMI

Nursing considerations
  • Strict inclusion/exclusion checklist — time-critical
  • Neuro checks and BP control on a tight schedule after
  • NO invasive procedures/punctures during and after per protocol
Key side effects
Bleeding (including intracranial)HypotensionReperfusion arrhythmias
📈 Watch

Neuro status, BP, bleeding — continuous

Source: Generic names only, per NCSBN convention. Primary sources: Lehne's Pharmacology for Nursing Care, 11th ed.; Davis's Drug Guide for Nurses. Educational reference — verify every medication decision against your facility's formulary, pharmacy, and the prescriber. Doses shown are typical adult references, not recommendations.Reference only — verify against your facility's policy.

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