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Thiazide Diuretics

-thiazide
How it works

Block sodium reabsorption in the distal tubule — milder than loops, first-line for blood pressure.

You'll see
hydrochlorothiazidechlorthalidone
Used for
Hypertension (first-line)Mild edema
Side effects
HypokalemiaHyponatremia (elderly!)Hyperglycemia, hyperuricemia (gout)Photosensitivity
Monitor
  • Electrolytes — the classic cause of the confused hyponatremic elderly patient
  • Glucose in diabetics
  • Ineffective when GFR is poor — loops take over
🎓 Patient teaching

Morning dose. Sunscreen. Gout patients: this can trigger a flare — report joint pain.

Source: Lehne's Pharmacology for Nursing Care, 11th ed.Reference only — verify against your facility's policy.

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