Statins
-statinHow it works
Block HMG-CoA reductase, the liver's cholesterol factory → LDL falls, plaque stabilizes.
You'll see
Used for
Side effects
Monitor
- New muscle pain + dark urine = check CK, hold and call — that's the rhabdo picture
- Baseline and PRN LFTs
🎓 Patient teaching
Report unexplained muscle pain, especially with brown urine. Often dosed in the evening (cholesterol synthesis peaks overnight). Avoid grapefruit with simvastatin/atorvastatin.
Source: Lehne's Pharmacology for Nursing Care, 11th ed.Reference only — verify against your facility's policy.